Bio

Victoria was born in Montevideo, Uruguay, and studied Biotechnology in the Polytechnic University of Valencia, Spain. She later did her master’s degree in Neuroscience at the Universitat Autònoma de Barcelona, and is now a graduate student in Mike Boxem’s group, in Utrecht University.

Project

Mike Boxem’s group is studying the process of cell polarization in epithelial tissues, and Victoria is focusing in the Crumbs apical complex. Crumbs complex proteins play a central role in establishing apical domain identity in epithelial cells in Drosophila and mammals and, in addition to its role in polarity, recent studies found that Crumbs has important roles in tissue morphogenesis and growth control. However, not all epithelial tissues require Crumbs functioning and in C. elegans the knockout of Crumbs proteins does not show obvious defects in tissue morphogenesis and polarity. Victoria hopes to improve our understanding of the role of Crumbs in controlling apical identity, as well as its interaction with other cellular processes important for cell polarity and epithelial functioning.