Welcome to PolarNet

Integrating genetic, biophysical and computational approaches
to understand cell and tissue polarity

Marie Skłodowska-Curie Actions Innovative Training Network 675407

OUR GOALS
Polarnet has three objectives

Research

PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary training and research programme. Through individual research projects, 15 early stage researchers (ESRs) will study the basic principles of cell polarity.


 

Teaching

Network-wide training events focused on cell polarity, biophysical and modelling approaches, transferable skills and personal development complement the high quality research training. Secondment opportunities ensure exposure to the private sector.


 

Outreach & Dissemination

PolarNet aims to inform the general public of its goals and activities through this website and outreach events organized by the ESRs and supervisors. Research results will be communicated in peer-reviewed scientific journals and at conferences.

Introducing…
RESEARCH GOALS
The individual projects address three main research goals

Fundamentals

Understanding how polarity emerges from interactions between individual components requires
mathematical modelling informed by experimentally determined parameters. Four research projects aim to better understand the fundamental principles that govern cell polarity.

Cortical polarity complexes

Mutual inhibitory interactions between protein complexes located at the cell cortex play a major role in cell polarity. Four research projects aim to obtain new insights into the roles of cortical polarity regulators in complex settings such as tissues or migrating cells.

Multicellular

In an organism, polarized cells rarely act in isolation, but are part of a larger tissue. Seven research projects study polarity in a multicellular context. Topics include integration of polarity and tissue mechanics, maintenance of tissue integrity, and use of new organoid models.

LATEST NEWS

3rd Annual Network Meeting held

On December 10 -14 2018, PolarNet held its 3rd Annual Meeting at the Technische Universität Dresden in beautiful (if a bit cold) Dresden! Our host, Prof. Stephan Grill and his team made sure that everything was very efficiently organized :-). All ESRs attended for the entire week, and enjoyed two very inspiring and educative workshops; […]

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BLOG POST

Robots at Abu Dhabi!

In November 2018, Amalia and Victoria visited New York University in Abu Dhabi (NYUAD) where they carried out their secondments in the lab of Dr. Kris Gunsalus. There, they took advantage of using a robotic platform to perform two whole-genome RNAi screens in C. elegans. The goal of the screens was to identify proteins that act redundantly […]

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