Welcome to PolarNet

Integrating genetic, biophysical and computational approaches
to understand cell and tissue polarity

Marie Skłodowska-Curie Actions Innovative Training Network 675407

Position available, click here for details

Polarnet has three objectives


PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary training and research programme. Through individual research projects, 15 early stage researchers (ESRs) will study the basic principles of cell polarity.


Network-wide training events focused on cell polarity, biophysical and modelling approaches, transferable skills and personal development complement the high quality research training. Secondment opportunities ensure exposure to the private sector.

Outreach & Dissemination

PolarNet aims to inform the general public of its goals and activities through this website and outreach events organized by the ESRs and supervisors. Research results will be communicated in peer-reviewed scientific journals and at conferences.

The individual projects address three main research goals


Understanding how polarity emerges from interactions between individual components requires
mathematical modelling informed by experimentally determined parameters. Four research projects aim to better understand the fundamental principles that govern cell polarity.

Cortical polarity complexes

Mutual inhibitory interactions between protein complexes located at the cell cortex play a major role in cell polarity. Four research projects aim to obtain new insights into the roles of cortical polarity regulators in complex settings such as tissues or migrating cells.


In an organism, polarized cells rarely act in isolation, but are part of a larger tissue. Seven research projects study polarity in a multicellular context. Topics include integration of polarity and tissue mechanics, maintenance of tissue integrity, and use of new organoid models.


Mid-term review held

On november 17, PolarNet held it’s mid-term review meeting at the Hotel Arena in Amsterdam. All ESRs and representative supervisors of each workpackage met with the EU project officer and an external reviewer, to discuss the progress of the network. In the morning, the coordinator and work package leaders presented an overview of PolarNet’s goals, […]



Secondment at Cardiff University – A German goes from the Netherlands to Wales

One of the very positive things about being part of the PolarNet network is that it stimulates international exchange among the participating groups. For example, it gives us, the PhD students, the great opportunity to visit another research group for a couple of weeks and learn new techniques, make new acquaintances and help us to […]