Welcome to PolarNet

Integrating genetic, biophysical and computational approaches
to understand cell and tissue polarity

Marie Skłodowska-Curie Actions Innovative Training Network 675407

OUR GOALS
Polarnet has three objectives

Research

PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary training and research programme. Through individual research projects, 15 early stage researchers (ESRs) will study the basic principles of cell polarity.

Teaching

Network-wide training events focused on cell polarity, biophysical and modelling approaches, transferable skills and personal development complement the high quality research training. Secondment opportunities ensure exposure to the private sector.

Outreach & Dissemination

PolarNet aims to inform the general public of its goals and activities through this website and outreach events organized by the ESRs and supervisors. Research results will be communicated in peer-reviewed scientific journals and at conferences.

RESEARCH GOALS
The individual projects address three main research goals

Fundamentals

Understanding how polarity emerges from interactions between individual components requires
mathematical modelling informed by experimentally determined parameters. Four research projects aim to better understand the fundamental principles that govern cell polarity.

Cortical polarity complexes

Mutual inhibitory interactions between protein complexes located at the cell cortex play a major role in cell polarity. Four research projects aim to obtain new insights into the roles of cortical polarity regulators in complex settings such as tissues or migrating cells.

Multicellular

In an organism, polarized cells rarely act in isolation, but are part of a larger tissue. Seven research projects study polarity in a multicellular context. Topics include integration of polarity and tissue mechanics, maintenance of tissue integrity, and use of new organoid models.

LATEST NEWS

PolarNet work presented WCCE10/ECAB4

Nuria Abajo Lima presented her work at Cardiff University and Cellesce at the combined 10th World congress of chemical engineering and 4th European symposium of applied biotechnology. Well done Nuria!

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BLOG POST

Polarity for Bachelor, Master and Highschool students

Education is very a important part of a PhD, and at Utrecht University we have the opportunity to supervise students at different  levels. This has been challenging but also fun and rewarding. My first experience with supervising was with 5 bachelor students. They were coming from two different programs, both Biology and Biomedical Sciences. They […]

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